Consent waivers play an important role in recruitment of critically ill adults into clinical trials


  • Consent waivers in research help to increase the proportion of critically ill adults able to participate in clinical trials.

Why this matters

  • Further research on critically ill individuals is urgently needed to improve their prognosis; however, it is difficult to involve this vulnerable population due to the difficulty of obtaining informed consent.

  • The 2014 update of the Swiss law on research increased individuals' protection by adding specific requirements for emergency situations, but the role of consent waivers is unclear.

  • These important findings suggest that consent waivers play a key role in recruitment of critically ill participants in clinical trials.