Correlation of collateral status with ischemic core growth in patients with acute ischemic stroke


  • Rate of ischemic core growth can independently predict clinical outcome following acute ischemic stroke, and collateral status is a major determinant of ischemic core growth.

Why this matters

  • Treatment of acute ischemic stroke by restoration of blood supply is dependent on blocking ischemic core growth rate, which is variable for the 72 h following acute ischemic stroke.

  • Ischemic core growth rate is reportedly an independent predictor of clinical outcome.

  • The relationship between collateral status and ischemic core growth rate remains unexplored.