Rate of ischemic core growth can independently predict clinical outcome following acute ischemic stroke, and collateral status is a major determinant of ischemic core growth.
Why this matters
Treatment of acute ischemic stroke by restoration of blood supply is dependent on blocking ischemic core growth rate, which is variable for the 72 h following acute ischemic stroke.
Ischemic core growth rate is reportedly an independent predictor of clinical outcome.
The relationship between collateral status and ischemic core growth rate remains unexplored.