Corticostriatal dysconnectivity may play a central role across the spectrum of psychosis

Takeaway

  • Healthy individuals with high schizotypy have hypoconnectivity in the striatum and the same brain regions previously identified in individuals with diagnosed schizophrenia.

Why this matters

  • It is unclear whether corticostriatal dysconnectivity occurs in individuals with high positive schizotypy in the absence of schizophrenia.