CSF synaptic biomarkers used to distinguish people with Alzheimer’s disease from those without

Takeaway

  • Synaptic biomarkers had good discriminatory power in distinguishing people with Alzheimer’s disease (AD) from those without AD.

Why this matters

    Synaptic loss is well recognized in AD, however, the utility of pre- and post-synaptic protein levels as diagnostic biomarkers for AD is not well characterized.