Damage to long-range brain connections impacts cognition in multiple sclerosis

Takeaway

  • Compared with multiple sclerosis (MS)-specific short-range connections in the brain, MS-specific damage to long-range connections is more severe and more strongly related with reduced efficiency of structural networks and impact on cognitive function.

Why this matters

  • These results better our understanding of how MS-specific damage brings about cognitive impairment and may inform future developments in understanding disease prognosis.

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