Deep brain stimulation and probabilistic stimulation mapping in movement and psychiatric disorders


  • Probabilistic stimulation maps (PSMs) identified specific subregions in the brain that are responsible for the optimal clinical responses during deep brain stimulation (DBS) in people with movement or psychiatric disorders.

Why this matters

  • DBS through electrodes implanted in precise locations the brain, is a well-established therapy for movement disorders and has been evaluated in some cognitive and psychiatric disorders.

  • Our current understanding of the optimal target and stimulation parameters for each indication is limited, and thus, magnetic resonance imaging (MRI)-based probabilistic maps can use clinical and imaging information to aid in refining DBS performance.