Deep brain stimulation lowers pain in people with Parkinson’s disease through analgesia activation

Takeaway

  • Deep brain stimulation (DBS) lowers pain sensitivity in people with Parkinson’s disease (PD), in part, through changes in the supplementary motor area (SMA) in association with subcortical/cortical sensory circuitry.

Why this matters

    Subthalamic deep brain stimulation (STN DBS) is an effective treatment for PD, but the mechanism which DBS modulates sensory function described in this study remains uncertain.