Deep gray matter and other abnormalities in pediatric acute-onset neuropsychiatric syndrome

Takeaway

  • Diffusion-weighted MRI identified microstructural abnormalities in the brains of children with pediatric acute-onset neuropsychiatric syndrome (PANS), including increased diffusivity in deep gray matter which may be consistent with inflammation.

Why this matters

    Results support further investigation of diffusion MRI as one quantitative tool in the resources for evaluation of possible PANS.