Depressive symptoms could be a marker of increased risk of progression from motoric cognitive risk syndrome to dementia


  • Depressive symptoms are a substantial predictor of conversion to dementia in elderly adults with motoric cognitive risk syndrome.

Why this matters ?

  • Motoric cognitive risk syndrome is linked to increased risk of incident dementia; however, clinical predictors of progression to dementia were previously unknown.

  • These novel findings suggest that certain characteristics, such as depression and lower cognitive activity, could predict those individuals most at risk of conversion. The findings highlight the need for early intervention of modifiable risk factors to prevent further deterioration in these individuals.