Detecting retinal microvascular changes in individuals with neuromyelitis optic spectrum disorder

Takeaway

  • Changes in retinal microcirculation can occur in individuals with neuromyelitis optic spectrum disorder (NMOSD) who have no history of optic neuritis (ON).

Why this matters

    Individuals with NMOSD and a history of ON (NMOSD+ON) have severe thinning of the peripapillary retinal nerve fiber layer (pRNFL) and the ganglion cell and inner plexiform layer (GCIPL), which are reliable biomarkers. The results of this study suggest certain retinal vascular parameters may act as reliable biomarkers to distinguish NMOSD eyes with no history of ON (NMOSD-ON) from healthy controls (HC).