Differences in peripheral nerves and muscle degeneration of spinal muscular atrophy subtypes


  • There are distinct differences in the cross-sectional area (CSA) of peripheral nerves and fatty muscle degeneration across 3 spinal muscular atrophy (SMA) subtypes.

Why this matters

    Quantitative magnetic resonance neurography (MRN) biomarkers in adults with SMA may provide earlier confirmation of therapeutic efficacy compared with current clinical and electrophysiological methods.