Differences in spinal cord magnetic resonance imaging features in children with acquired demyelinating syndromes


  • Characteristic imaging features may be helpful in identifying specific underlying causes of pediatric acquired demyelinating syndromes.

Why this matters

  • Pediatric acquired demyelinating syndromes, such as pediatric myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), multiple sclerosis (MS), and seronegative myelitis, regularly affect the spinal cord.

  • Magnetic resonance imaging (MRI) is often involved in the diagnostic procedure, which can reveal characteristic imaging features for different conditions.

  • However, the data comparing characteristic imaging features for spinal cord lesions in children and adolescents with MOGAD, MS, and seronegative myelitis are outdated and require reevaluation.