Distinct brain activity while reading in semantic variant primary progressive aphasia

Takeaway

  • People with semantic variant primary progressive aphasia engage the sublexical/phonological route when reading both irregular and pseudowords.

Why this matters

    This is the first investigation of its kind. By combining a neuropsychological model and time-resolved magnetoencephalography imaging, the authors uncover a dual-route model for reading aloud. Task-based magnetoencephalography imaging could be used to study the functional interplay of specific language networks and this will have significant implications for clinical practice.