Distinct order of cognitive decline in typical Alzheimer’s disease and posterior cortical atrophy


  • Cognitive decline differs between two types of dementia which is vision-led in posterior cortical atrophy and memory-led in typical Alzheimer’s disease.

Why this matters

    This is the first direct comparison of the sequence of cognitive decline in posterior cortical atrophy and typical Alzheimer’s disease; the findings support clinical opinion on disease progression. In clinical practice, this improved understanding could facilitate earlier differential diagnosis and prognosis.