Does mild traumatic brain injury impact pain modulation?


  • Mild traumatic brain injury (mTBI) increases trigeminal sensitization, decreases pain inhibition and is linked to greater levels of depression and pain catastrophizing in the first 2 weeks following injury.

Why this matters

  • TBI – a common cause of disability ­– could result in maladaptive pain modulation; as such, individuals with injury may have increased pain management needs.