Dynamics of functional connectivity states in those with Parkinson’s disease

Takeaway

  • Those with Parkinson’s disease (PD) more frequently experienced a segregated brain state than healthy individuals, and this brain state was associated with increased cognitive impairment.

Why this matters ?

    Assessment of temporal dynamics of functional connectivity (e.g., fractional windows, dwell time, and number of transitions between states) may be used as an imaging biomarker to monitor cognitive changes in those with PD.