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Early detection of Alzheimer's disease: promising new methods?

 

Introduction

According to the 2015 World Alzheimer Report, there are approximately 46 million people worldwide living with dementia.1 This number is expected to double every 20 years, reaching 131.5 million by 2050.1 It has been estimated that the total worldwide dementia-related healthcare cost is $818 billion, rising to $2 trillion by 2030.1 Alzheimer’s disease (AD) is the most common progressive cause of dementia in the elderly and a severe public health burden on the aging society, especially as life expectancy increases in certain parts of the world.1 As part of the top 10 leading causes of death in America, AD has no proven preventive or curative interventions.2 Progress in the management and treatment of AD is limited by lack of early diagnostics, yet early diagnosis is critical to the development of effective therapies. Although there are anti-