Effect of early monocular enucleation in the auditory system


  • Early blindness in one eye from monocular enucleation leads to white matter structural changes in the auditory system in adulthood.

Why this matters

  • Monocular enucleation during early brain development can lead to crossmodal effects in adulthood; for example, people with monocular enucleation have demonstrated improved sound localization skills.

  • People with monocular enucleation have changes in white matter structure in the visual system; however, the specific changes in the auditory system are not known, and understanding these changes may lead to improved clinical outcomes.