Effect of sleep deprivation on functional connectivity and cognitive performance


  • Sleep deprivation (SD) is associated with a significantly reduced task-related decrease in functional connectivity, which, in turn, is significantly associated with changes in cognitive performance.

Why this matters

  • Up to 39% of adults aged 18–65 years suffer from SD, which has a significant negative impact on their cognitive function.

  • Neuroimaging studies have shown decreased local and global neuronal activity associated with SD, but the mechanisms involved are not fully understood.

  • This is the first published study that used the functional near-infrared spectroscopy (fNIRS) to assess the effect of SD on resting-state and task-related functional connectivity of the frontal lobe.