Effect of vitamin D use in people with multiple sclerosis

Takeaway

  • People with multiple sclerosis (MS) who have vitamin D levels above 30 ng/ml have preserved myelin compared to people with MS who have levels below 30 ng/ml.

Why this matters

  • Vitamin D deficiency is associated with increased risk of relapsing remitting MS (RRMS); however, there are limited data about the association between vitamin D and primary progressive MS (PPMS) and secondary progressive MS (SPMS).

  • Additionally, there is an increase in lesion formation in people with MS who have a vitamin D deficiency; however, there have been mixed clinical outcomes from vitamin D supplementation.

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