Effects of oxycodone and gabapentin on acute pain responses when added to buprenorphine or methadone


  • Addition of an opioid or gabapentin to methadone- or buprenorphine-maintained people did not improve objective measures of analgesia.

Why this matters

  • Long-term pain management with opioids is challenging and there is considerable interindividual variability in response, further research is required to optimize pain management strategies.

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