Effects of subthalamic DBS on motor learning in Parkinson’s

Takeaway

  • Deep brain stimulation (DBS) can help restore motor learning function in patients with Parkinson’s disease (PD), possibly via modulation of a subcortical network with connectivity to cerebellar lobule VII in addition to modulation of cortical circuits.

Why this matters ?

  • The motor and cognitive effects of subthalamic nucleus (STN)-DBS, an established treatment for advanced Parkinson’s disease, are thought to stem from stimulation of differential neural pathways.

  • Findings from this study provide new insight into the circuit nature of Parkinson’s disease and the distributed network effects of deep brain stimulation in motor learning.