Electroencephalography to evaluate total corpus callosotomy prognosis for infantile spasms


  • Interictal epileptic discharges measured by electroencephalography (EEG) may indicate likelihood of seizure reduction following total corpus callosotomy (TCC) in children with pharmacoresistant infantile spasms (IS).

Why this matters

  • Some children with IS achieve freedom from seizures after 1 surgery, and some have persistent seizure activity after multiple surgeries.

  • Correlations between interictal epileptic discharge patterns and TCC outcomes could guide IS surgical treatment decisions.