Epilepsy with myoclonic atonic seizures: morphometric analysis of brain structures


  • Structural brain abnormalities were detected in children with epilepsy with myoclonic atonic seizure (EMAS) when compared to healthy controls.

Why this matters

  • EMAS is a rare pediatric epilepsy syndrome with variable outcomes, ranging from seizure freedom and normal intelligence to refractory epilepsy with intellectual disability.

  • The pathophysiological mechanisms underlying EMAS remain unknown. This is the first study to use quantitative brain MRI analysis to identify structural abnormalities in EMAS.