Epileptiform events during cortical activation in people with generalized epilepsy

Takeaway

  • High-density electroencephalography (HdEEG) recordings are practical, effective, and safe in a myoclonic epilepsy mouse model.

Why this matters

  • On EEG recordings, general seizures appear to engage all brain areas and lack discrete targetable regions; however, advanced neurophysiological techniques have revealed the preferential engagement of specific brain regions.

  • This study identifies unique regions and processes that could be targeted for further modulation.