Ethnic differences in individuals with neuromyelitis optic spectrum disorder in Toronto, Canada


  • Asian individuals with neuromyelitis optica spectrum disorder from Toronto, Canada were more likely than blacks to demonstrate classic NMO by 2006 diagnostic criteria and had a poorer long-term disability outcome compared with Caucasians.

Why this matters

  • Recent international studies suggest that the ethnicity of an individual with NMOSD may be predictive of their disease outcome and relapse type. These studies were limited as they investigated the effects of ethnicity in homogeneous populations from different countries.

  • The results of this study could help identify prognostic factors in NMOSD, with ethnically similar individuals in the same region, which are essential for selecting appropriate therapies.