Evaluating brain morphology and psychological disorders in traumatic brain injury and psychogenic nonepileptic seizures

Takeaway

  • People with traumatic brain injury and psychogenic nonepileptic seizures (TBI-PNES) have brain atrophy and aberrant cortical folding in brain regions contributing to emotional regulation.

Why this matters

  • Few studies have evaluated the relationship between brain structure and function in patients with PNES.

  • Results from this study suggest that environmental, developmental, and neurobiological factors may all contribute to PNES, providing potential guidance for management of PNES.