Evaluation of autonomic nervous system impairment in amyotrophic lateral sclerosis


  • The autonomic nervous system was not impaired in patients with amyotrophic lateral sclerosis (ALS), despite higher non-motor symptom (NMS) load.

Why this matters

  • While ALS is well characterized by upper and lower motor neuron degeneration, the extent of autonomic changes in ALS is not well understood.

  • Understanding autonomic changes in ALS may help with future treatment approaches but results of this study suggest that patients with ALS do not have an impaired autonomic nervous system.