Evaluation of blood pressure alterations in patients with different stages and subtypes of Parkinson’s disease


  • In Parkinson’s disease (PD) patients, reverse blood pressure (BP) dipping is more common, particularly during advanced disease. 

Why this matters

  • Abnormal BP is associated with PD, and it is thought that BP abnormalities are more common in non-tremor-dominant PD; thus, detection of abnormal BP may help with earlier diagnosis of PD. Detection and treatment of BP abnormalities may also help prevent other serious conditions that can lead to harm in patients with PD.

  • This study suggests that reverse nocturnal BP dipping is evidence of cardiovascular dysautonomia in PD and supports the use of 24-hour BP monitoring and BP treatment in people with PD.