Evaluation of retinal microvascular alterations associated with ataxias

Takeaway

  • Inherited and sporadic ataxias are associated with specific microvascular retinal changes compared to healthy controls that can be detected using optical coherence tomography angiography (OCT-A).

Why this matters ?

  • Occurrence and timing of microvascular alterations in relationship to neurodegenerative diseases are not well studied.

  • Results from this study suggest that therapy for ataxias should include measures to reduce neuronal injury and the resulting neurological disability.