Evaluation of retinal microvascular alterations associated with ataxias

Takeaway

  • Inherited and sporadic ataxias are associated with distinct microvascular retinal changes that can be detected using optical coherence tomography angiography (OCT-A).

Why this matters

  • Occurrence and timing of microvascular alterations in relationship to neurodegenerative diseases are not well studied. Results from this study suggest that therapy for ataxias should include measures to reduce neuronal injury and the resulting neurological disability.