Evaluation of the inverse relationship between cancer and Alzheimer’s disease

Takeaway

  • People with a history of cancer have a lower risk of Alzheimer’s disease (AD) than those with no cancer history, which is unlikely due to diagnostic bias, competing risks bias, or insufficient or inappropriate control for potential confounding factors.

Why this matters

    Several observational studies have reported an inverse association between cancer and AD, and it is theorized that methodological biases may contribute. Understanding this association may aid in improving diagnosis and treatment outcomes in both diseases.