Evidence of acquired trans-synaptic retrograde axonal degeneration in the visual system

Takeaway

  • Acquired retrograde trans-synaptic axonal degeneration (RTD) was found to affect the retinal nerve fiber layer, ganglion cell and inner plexiform layer.

Why this matters

  • To date, no conclusive evidence has been reported for the presence of acquired RTD in the visual system. This study provides evidence that helps demonstrate its existence and may provide an avenue to improve visual outcomes.