Examining genetic variants in leukocyte trafficking and association with multiple sclerosis


  • Variants of genes encoding adhesion molecules involved in lymphocyte access and trafficking in the central nervous system are associated with risk of developing multiple sclerosis (MS).

Why this matters

  • The results of this study could provide physicians with a patient-personalized tool to aid diagnosis and treatment of MS, particularly in those who present to the clinic with clinically or radiologically isolated symptoms.