Exploring the association between benign prostatic hyperplasia and risk of motor neuron disease

Takeaway

  • No association was found between benign prostatic hyperplasia (BPH) and risk of amyotrophic lateral sclerosis (ALS) or other motor neuron disease (MND).

Why this matters

  • BPH often causes sleep disturbance; thus, an increased risk of MND in BPH patients could support the link between sleep disruption in and development of MND such as ALS.

  • While sleep disturbance is considered a risk factor for MND, its association has not been previously explored.