Exploring the effect of post-endovascular thrombectomy blood pressure on outcomes in patients with acute ischemic stroke


  • In patients undergoing endovascular thrombectomy (EVT) for anterior circulation large vessel occlusion (LVO), high post-EVT mean systolic blood pressure (SBP) levels are associated with higher odds of adverse outcomes and mortality, and recanalization status after EVT did not modify these associations.

Why this matters

  • Approximately half of patients achieving successful post-EVT reperfusion die or suffer disability, and blood pressure (BP) may be a potential contributor.

  • While guidelines recommend BP thresholds, they lack substantiation by clinical trials; thus, there are limited data available to guide BP management in this patient population.

  • This study suggests that further studies are needed to identify optimal SBP targets following EVT, towards improving stroke outcomes.