Exploring unawareness of memory loss in pre-clinical Alzheimer’s disease


  • Altered self-awareness of memory loss is associated with amyloid-β (Aβ) burden in pre-clinical Alzheimer’s disease (AD) and unawareness can be detected 3 years before progression to dementia.

Why this matters

    Unawareness (anosognosia) of memory abilities is common in patients with dementia, yet there is limited consensus regarding the presence and evolution of this symptom during the early stages of AD.

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