Exploring word comprehension after atrophy–deficit in the temporal cortex and Wernicke area

Takeaway

  • The Wernicke area has an ancillary but not essential role in single word comprehension; an intact Wernicke area cannot sustain word comprehension in primary progressive aphasia (PPA) patients.

Why this matters ?

    Prior investigations in patients with primary progressive aphasia and semantic dementia have associated comprehension impairments with atrophy in anterior temporal (AT) cortices rather than the Wernicke area.