Exposure to fine particulate matter during neurodevelopment in rats


  • Neurodevelopment in the early postnatal period in immature and mature rats is impaired due to disruption of the structural synaptic plasticity in immature and mature rats.

Why this matters

  • Fine particle matter (PM2.5) is closely associated with neurological disorders but its effect on neurodevelopment is unclear.
  • Exposing immature and mature rats in the early postnatal period to PM2.5 may demonstrate its effect on emotional and cognitive development.