Tumor control in patients with craniopharyngioma was significantly improved when at least 85% of the tumor received ≥12 Gy radiation.
Why this matters
Craniopharyngiomas are slow-growing, rare, and complex tumors, located near the optic apparatus, pituitary stalk, and critical vascular structures.
Stereotactic radiosurgery (SRS) is a minimally invasive treatment modality for newly diagnosed, recurrent, or residual craniopharyngiomas.
However, the optimal radiation dose delivered for maximal tumor control, while minimizing radiation to adjacent brain structures, remains elusive.