Family-based whole genome sequencing plays powerful role in genetic diagnosis of epilepsy

New study findings support the powerful role of family/trio-based whole genome sequencing (WGS) in the genetic diagnosis of epilepsy, particularly in the case of early-onset epilepsy (EOE).

Dr Yo-Tsen Liu of the Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, presented the results of a study showing the value of family/trio-based WGS (typically a trio of a mother, father, and child) in the genetic diagnosis of epilepsy. The aim was to investigate the utility of WGS and evaluate its cost-effectiveness in the genetic diagnosis of different epilepsy syndromes.