Frequency-specific abnormal spontaneous neural activity associated with tension-type headache


  • In tension-type headache (TTH), abnormal spontaneous neural activity is frequency specific.

Why this matters

  • TTH is frequent and causes significant impact on daily life; thus, understanding its pathophysiology is likely to have positive impacts on global health.

  • Some studies have suggested a relationship between activity alterations in brain regions of the descending brain pathway and TTH, but they have mainly focused on the conventional frequency band.

  • Results from this study provide insight into causes of TTH and may have implications for future treatment directions.