Right temporal lobe epilepsy (rTLE) patients have significantly altered patterns of brain entropy compared to healthy controls; in addition, intrinsic and phasic alertness are positively associated with decreasing brain entropy in the right precentral gyrus.
Altered brain entropy may be associated with a reconstruction of brain functional connectivity in patients with rTLE.
Why this matters ?
Entropy is a known non-linear parameter that has been used to characterize brain states through analysis of electrophysiological data. It has been shown to be significantly higher during seizures in people with epilepsy; changes in alertness also affect entropy.