GBA carrier variants and Parkinson’s disease risk

Takeaway

  • The risk of Parkinson’s disease (PD) is increased in GBA carriers, especially those with variants near the SNCA or CTSB loci.

Why this matters

  • This study supports further investigation of SNCA and CTSB for functional analysis in PD and highlights the potential impact of the lysosomal pathway in PD.

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