Summary Summary Short summary of a recent publication, written by scientific experts. Published: Dec 03, 2019

GBA carrier variants and Parkinson’s disease risk

Takeaway

  • The risk of Parkinson’s disease (PD) is increased in GBA carriers, especially those with variants near the SNCA or CTSB loci.

Why this matters

    This study supports further investigation of SNCA and CTSB for functional analysis in PD and highlights the potential impact of the lysosomal pathway in PD.