Genetic contribution to brain magnetic resonance imaging measures is unique to distinct types of multiple sclerosis

Takeaway

  • Associations between magnetic resonance imaging and functional processes differ between progressive versus relapsing-remitting forms of multiple sclerosis.

Why this matters

  • Little is known about genetic determinants of disease expression in multiple sclerosis; this is the first study to explore the genetic contribution of magnetic resonance imaging measurements in selected brain regions.

  • These novel findings further our understanding of the impact of genetic variation on imaging phenotype early in multiple sclerosis.