Genetic factors exacerbating risk of Alzheimer’s Disease

Takeaway

  • Women carrying the apolipoprotein E (APOE) ε4 mutation are at a higher risk of developing Alzheimer’s Disease (AD).

Why this matters

    Sex-linked risk factor APOEε4 can be used to help identify at-risk populations and should also be taken into account when APOEε4 forms the basis of inclusion criteria in clinical trial settings.