Genetic links between multiple sclerosis and depression

Takeaway

  • The single nucleotide polymorphism (SNP) rs1432639 and the IGF1 pathway suggest a genetic link between multiple sclerosis (MS) and depression that warrants further research.

Why this matters

    Depression is a common co-morbidity in many individuals with MS; however, few studies have investigated the genetic determinants of depression in people with MS.