Genetic variants of adhesion molecules are associated with multiple sclerosis predisposition

Takeaway

  • Variants of genes involved in leukocyte trafficking into the central nervous system, most significantly SELP, ITGA4, and FN1, are associated with multiple sclerosis (MS) predisposition.

Why this matters

  • Further investigation of additional genetic factors that predispose to MS may provide physicians with personalized tools for diagnosis and treatment.