Hematopoietic stem cell transplantation as a potential rescue treatment for neuromyelitis optica

Takeaway

  • Autologous hematopoietic stem cell transplantation (HSCT) prolonged relapse-free and treatment free remission in most individuals with neuromyelitis optica spectrum disorder (NMOSD).

Why this matters

    Few treatments exist for individuals with NMOSD and many remain on immunosuppressive treatments between acute neurological attacks. The results of this study suggest that an autologous nonmyeloablative HSCT may be a potential treatment for individuals with neuromyelitis optica.