Quantitative susceptibility mapping reveals a connection between cerebral microbleeds and small veins in cerebral small vessel disease.
Why this matters
Microbleeds in the brain are a common occurrence in cerebral small vessel disease but their pathophysiology is unknown. The use of quantitative susceptibility mapping-based venograms at submillimeter resolution enabled the first in vivo study of venous contribution to the formation of cerebral microbleeds. The findings reveal that these microbleeds derive from veins, as well as arteries, which helps further our understanding of small vessel disease.