Hippocampal and amygdala volumes and oxytocin levels in the elderly


  • A positive correlation was observed between oxytocin levels and reduced hippocampal and amygdala volumes over the course of 7 years in individuals aged over 65 years.

Why this matters

  • Oxytocin plays a role in positive social interactions and in the reduction of oxidative stress and inflammation; reduced volume in oxytocin receptor-rich regions including the hippocampus and amygdala are implicated in aging and Alzheimer’s Disease (AD).

  • This correlation observed in this study indicates that oxytocin could be a potential predictive marker for age-related cognitive decline and AD in people over 65 years.